I'm in the US now visiting Mom. I'd downloaded the Garmin routable maps from Lambertus for California and uploaded to my Garmin eTrek Vista HCx. Before I left Thailand I played with these maps using Garmin Road Trip (Mac). The routing seemed to work just fine.
However, when trying to drive from the San Fernando Valley (LA, California) to Vasquez Rocks, northeast of LA I ran into massive trouble. The routing started out fine, heading us up Interstate 5 and over to California route 14; the same route I'd pick looking at a paper map.
But then, about half way there, the GPSr said to get off the highway. At first I figured this was the "shortest route" that I'd specified, but I soon realized that things were seriously amiss. The GPSr was advising us start heading back south to Interstate 5, the exact opposite direction from our goal. And, when I looked at the GPSr map, I realized that areas south of us were being displayed as being north of us. In short, it seemed that map tiles were either swapped (north for south) or overlapped. I guess this caused the routing peculiarities.
I turned navigation "off" and continued on with the paper map.
Once we got out of the overlap area things seemed back to normal.
I'm away from home and don't have any Garmin software available, so I can't explore this more fully. Will look again when I'm back in Thailand.