The latest release of tangoGPS now allows for downloading routes from http://yournavigation.org and from http://openrouteservice.org. Not a turn by turn navigation but still a quite nifty feature.
Apart from that the user interface has been improved, it looks now pretty good on laptops and even larger desktop LCDs too!
tangoGPS can be found on http://tangogps.org and feedback is always welcome.
Discussion
Comment from Komяpa on 22 November 2009 at 20:32
Is CloudMade planned?
Comment from marcusb on 23 November 2009 at 00:05
If you have a URL that is publically accessible I'll add it.